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Johnny Depp missed out on several major movie roles, some of which are classics. Depp could have played Ferris Bueller in 'Ferris Bueller's Day Off' (part went to Matthew Broderick), Jack Dawson in 'Titanic' (part went to Leonardo DiCaprio), John Smith in 'Mr. and Mrs. Smith' (part went to Brad Pitt) and Neo in 'The Matrix' (part went to Keanu Reeves).
Pictured: Johnny Depp (center) in 2009 during the premiere of 'Public Enemies.' Brad Pitt (bottom left) appears in a scene from 'Mr. and Mrs. Smith.' Keanu Reeves (upper left) appears in a scene from 'The Matrix.' Matthew Broderick (bottom right) appears in a scene from 'Ferris Bueller's Day Off.' Leonardo DiCaprio (upper right) appears in a scene from 'Titanic.'
( Photo / flickr.com/photos/nicogenin | Regency Enterprises | Warner Bros. Pictures | Paramount Pictures | Twentieth Century Fox Film Corporation)