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While filming 'Mr. Magorium's Wonder Emporium,' Natalie met a five year old child who was diagnosed with Bloom syndrome, a genetic disorder that can cause disabilities and has a high risk of cancer. Natalie was so touched that she arranged for a fashion auction benefitting research for a cure. Pictured: Dustin Hoffman and Natalie Portman in a scene from 'Mr. Magorium's Wonder Emporium.'
(Photo courtesy of Film Colony)