'The Simpsons' spoilers: Season 22 to feature Daniel Radcliffe, Facebook creator Mark Zuckerberg, more

08/03/2010 by Corinne Heller

The Simpsons is set to feature the voices of celebrities such as Harry Potter actor Daniel Radcliffe, Facebook creator Mark Zuckerberg, Mad Men's Jon Hamm and Glee stars Lea Michele, Cory Monteith and Amber Riley in the upcoming 22nd season, which is set to premiere on September 26 on FOX.

Check out what is in store this fall on the longest-running comedy and primetime series. Warning: Spoiler alert!

Other stars set to voice characters or themselves on the series include House actor Hugh Laurie, Halle Berry, comedian Ricky Gervais, Jemaine Clement and Bret McKenzie of Flight of the Conchords, Mark Zuckerberg, baseball legend Mike Scioscia, Martha Stewart, Paul Rudd, Rachel Weisz, comedy duo Cheech and Chong, Kristen Wiig, sports writer Bill James, Alyson Hannigan, NASCAR driver Danica Patrick, Kareem Abdul-Jabbar and Joe Mantegna, FOX said in a statement.

The season premiere episode, titled "Elementary School Musical," sees Clement and McKenzie playing counselors and the Glee stars voicing "musically inclined campers" at a performing arts camp Lisa Simpson attends.

"After she returns to Springfield, Lisa becomes restless with her ho-hum suburban lifestyle and catches the first bus to Sprooklyn in hopes of reconnecting with her inner hipster," the statement said.

Laurie and Radcliffe provide voices in the 21st annual "Treehouse of Horror" Halloween special. Other episodes see Hamm portraying an FBI agent and Stewart portraying herself in "The Fight Before Christmas," which features live-action puppets. Joe Mantegna returns as mobster Fat Tony.

Homer Simpson was last month named the greatest character created for television and film in the past 20 years by Entertainment Weekly magazine. Radcliffe, who recently filmed the final Harry Potter film and will return to Broadway next year to make his musical debut, was No. 2.

The Simpsons premiered in 1987. Homer Simpson, the dim-witted, doughnut-eating and Duff Beer-guzzling patriarch of the family show, is voiced by Dan Castellaneta.